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PreviewIssue DateTitleAuthor(s)
2017Knockout of the epilepsy gene Depdc5 in mice causes severe embryonic dysmorphology with hyperactivity of mTORC1 signallingHughes, J.; Dawson, R.; Tea, M.; McAninch, D.; Piltz, S.; Jackson, D.; Stewart, L.; Ricos, M.; Dibbens, L.; Harvey, N.; Thomas, P.
2017DR5 and caspase-8 are dispensable in ER stress-induced apoptosisGlab, J.; Doerflinger, M.; Nedeva, C.; Jose, I.; Mbogo, G.; Paton, J.; Paton, A.; Kueh, A.; Herold, M.; Huang, D.; Segal, D.; Brumatti, G.; Puthalakath, H.
2017Betamethasone-exposed preterm birth does not impair insulin action in adult sheep.De Matteo, R.; Hodgson, D.; Bianco-Miotto, T.; Nguyen, V.; Owens, J.; Harding, R.; Allison, B.; Polglase, G.; Black, M.; Gatford, K.
2017A ZEB1-miR-375-YAP1 pathway regulates epithelial plasticity in prostate cancerSelth, L.; Das, R.; Townley, S.; Coutinho, I.; Hanson, A.; Centenera, M.; Stylianou, N.; Sweeney, K.; Soekmadji, C.; Jovanovic, L.; Nelson, C.; Zoubeidi, A.; Butler, L.; Goodall, G.; Hollier, B.; Gregory, P.; Tilley, W.
2017Targeting sphingosine kinase 1 induces MCL1-dependent cell death in acute myeloid leukemia.Powell, J.; Lewis, A.; Zhu, W.; Toubia, J.; Pitman, M.; Wallington-Beddoe, C.; Moretti, P.; Iarossi, D.; Samaraweera, S.; Cummings, N.; Ramshaw, H.; Thomas, D.; Wei, A.; Lopez, A.; D'Andrea, R.; Lewis, I.; Pitson, S.
2017USP9X deubiquitylating enzyme maintains RAPTOR protein levels, mTORC1 signalling and proliferation in neural progenitorsBridges, C.; Tan, M.; Premarathne, S.; Nanayakkara, D.; Bellette, B.; Zencak, D.; Domingo, D.; Gecz, J.; Murtaza, M.; Jolly, L.; Wood, S.
2017Autoinducer 2 signaling via the phosphotransferase FruA drives galactose utilization by streptococcus pneumoniae, resulting in hypervirulenceTrappetti, C.; McAllister, L.; Chen, A.; Wang, H.; Paton, A.; Oggioni, M.; McDevitt, C.; Paton, J.; McDaniel, L.
2017A mutation in the viral sensor 2’-5’-oligoadenylate synthetase 2 causes failure of lactationOakes, S.R.; Gallego-Ortega, D.; Stanford, P.M.; Junankar, S.; Au, W.W.Y.; Kikhtyak, Z.; von Korff, A.; Sergio, C.M.; Law, A.M.K.; Castillo, L.E.; Allerdice, S.L.; Young, A.I.J.; Piggin, C.; Whittle, B.; Bertram, E.; Naylor, M.J.; Roden, D.L.; Donovan, J.; Korennykh, A.; Goodnow, C.C.; et al.; Wells, C.A.
2017Disrupting androgen receptor signaling induces Snail-mediated epithelial-mesenchymal plasticity in prostate cancerMiao, L.; Yang, L.; Li, R.; Rodrigues, D.; Crespo, M.; Hsieh, J.; Tilley, W.; De Bono, J.; Selth, L.; Raj, G.

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