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PreviewIssue DateTitleAuthor(s)
2013Linaclotide inhibits colonic nociceptors and relieves abdominal pain via guanylate cyclase-c and extracellular cyclic guanosine 3′,5′-monophosphateCastro, J.; Harrington, A.; Hughes, P.; Martin, C.; Ge, P.; Shea, C.; Jin, H.; Jacobson, S.; Hannig, G.; Mann, E.; Cohen, M.; MacDougall, J.; Lavins, B.; Kurtz, C.; Silos-Santiago, I.; Johnston, J.; Blackshaw, L.; Brierley, S.
2017Knockout of the epilepsy gene Depdc5 in mice causes severe embryonic dysmorphology with hyperactivity of mTORC1 signallingHughes, J.; Dawson, R.; Tea, M.; McAninch, D.; Piltz, S.; Jackson, D.; Stewart, L.; Ricos, M.; Dibbens, L.; Harvey, N.; Thomas, P.
2017NAD deficiency, congenital malformations, and niacin supplementationShi, H.; Enriquez, A.; Rapadas, M.; Martin, E.; Wang, R.; Moreau, J.; Lim, C.; Szot, J.; Ip, E.; Hughes, J.; Sugimoto, K.; Humphreys, D.; McInerney-Leo, A.; Leo, P.; Maghzal, G.; Halliday, J.; Smith, J.; Colley, A.; Mark, P.; Collins, F.; et al.
2017DR5 and caspase-8 are dispensable in ER stress-induced apoptosisGlab, J.; Doerflinger, M.; Nedeva, C.; Jose, I.; Mbogo, G.; Paton, J.; Paton, A.; Kueh, A.; Herold, M.; Huang, D.; Segal, D.; Brumatti, G.; Puthalakath, H.
2012Myb-binding protein 1A (MYBBP1A) is essential for early embryonic development, controls cell cycle and mitosis, and acts as a tumor suppressorMori, S.; Bernardi, R.; Laurent, A.; Resnati, M.; Crippa, A.; Gabrieli, A.; Keough, R.; Gonda, T.; Blasi, F.; Plow, E.
2013Migalastat HCl reduces globotriaosylsphingosine (Lyso-Gb3) in fabry transgenic mice and in the plasma of fabry patientsYoung-Gqamana, B.; Brignol, N.; Chang, H.; Khanna, R.; Soska, R.; Fuller, M.; Sitaraman, S.; Germain, D.; Giugliani, R.; Hughes, D.; Mehta, A.; Nicholls, K.; Boudes, P.; Lockhart, D.; Valenzano, K.; Benjamin, E.; Schiffmann, R.
2012Innate transcriptional networks activated in bladder in response to uropathogenic Escherichia coli drive diverse biological pathways and rapid synthesis of IL-10 for defense against bacterial urinary tract InfectionDuell, B.; Carey, A.; Tan, C.; Cui, X.; Webb, R.; Totsika, M.; Schembri, M.; Derrington, P.; Irving-Rodgers, H.; Brooks, A.; Cripps, A.; Crowley, M.; Ulett, G.
2016Topical application of fingolimod perturbs cutaneous inflammationSun, W.Y.; Dimasi, D.P.; Pitman, M.R.; Zhuang, Y.; Heddle, R.; Pitson, S.M.; Grimbaldeston, M.A.; Bonder, C.S.
2014Zinc and zinc transporters in macrophages and their roles in efferocytosis in COPDHamon, R.; Homan, C.; Tran, H.; Mukaro, V.; Lester, S.; Roscioli, E.; Bosco, M.; Murgia, C.; Ackland, M.; Jersmann, H.; Lang, C.; Zalewski, P.; Hodge, S.; Adlard, P.A.
2011The Lin28/let-7 axis regulates glucose metabolismZhu, H.; Shyh-Chang, N.; Segre, A.; Shinoda, G.; Shah, S.; Einhorn, W.; Takeuchi, A.; Engreitz, J.; Hagan, J.; Kharas, M.; Urbach, A.; Thornton, J.; Triboulet, R.; Gregory, R.; DIAGRAM Consortium,; MAGIC Investigators,; Altshuler, D.; Daley, G.