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PreviewIssue DateTitleAuthor(s)
2001The protein tyrosine phosphatase TCPTP suppresses the tumorigenicity of glioblastoma cells expressing a mutant epidermal growth factor receptorKlingler-Hoffmann, M.; Fodero-Tavoletti, M.; Mishima, K.; Narita, Y.; Cavenee, W.; Furnari, F.; Huang, H.; Tiganis, T.
2014Differential, dominant activation and inhibition of Notch signalling and APP cleavage by truncations of PSEN1 in human diseaseNewman, M.; Wilson, L.; Verdile, G.; Lim, A.; Khan, I.; Nik, S.; Pursglove, S.; Chapman, G.; Martins, R.; Lardelli, M.
2012Guanylate cyclase-C receptor activation: unexpected biologyBrierley, S.
2001Peptide insertions in domain 4 of hbc, the shared signalling receptor subunit for GM-CSF, IL3 and IL5, induce ligand-independent activationJones, K.; Bagley, C.; Butcher, C.; Barry, S.; Vadas, M.; D'Andrea, R.
2005Phosphorylation-dependent translocation of sphingosine kinase to the plasma membrane drives its oncogenic signallingPitson, S.; Xia, P.; Leclercq, T.; Moretti, P.; Zebol, J.; Lynn, H.; Wattenberg, B.; Vadas, M.
2008NFκB selectivity of estrogen receptor ligands revealed by comparative crystallographic analysesNettles, K.; Bruning, J.; Gil, G.; Nowak, J.; Sharma, S.; Hahm, J.; Kulp, K.; Hochberg, R.; Zhou, H.; Katzenellenbogen, J.; Katzenellenbogen, B.; Kim, Y.; Joachimiak, A.; Greene, G.
2010Coupling of receptor conformation and ligand orientation determine graded activityBruning, J.; Parent, A.; Gil, G.; Zhao, M.; Nowak, J.; Pace, M.; Smith, C.; Afonine, P.; Adams, P.; Katzenellenbogen, J.; Nettles, K.
2008Re-evaluating the roles of proposed modulators of mammalian target of rapamycin complex 1 (mTORC1) signalingWang, X.; Fonseca, B.; Tang, H.; Liu, R.; Elia, A.; Clemens, M.; Bommer, U.; Proud, C.
2005Structural and functional characteristics of the Val44Met insulin-like growth factor I missense mutation: Correlation with effects on growth and developmentDenley, A.; Wang, C.; McNeil, K.; Walenkamp, M.; van Duyvenvoorde, H.; Wit, J.; Wallace, J.; Norton, R.; Karperien, M.; Forbes, B.