Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/129014
Citations | ||
Scopus | Web of Science® | Altmetric |
---|---|---|
?
|
?
|
Type: | Journal article |
Title: | Prevalence of self-reported polycystic ovary syndrome and profiles of health among women of different generations: a cross sectional study |
Author: | Avery, J.C. Moran, L. Moore, V. Fernandez, R. Whitrow, M. Stocks, N. Gill, T. Musker, M. Rumbold, A. |
Citation: | Fertility & Reproduction, 2019; 1(3):141-147 |
Publisher: | World Scientific |
Issue Date: | 2019 |
ISSN: | 2661-3182 2661-3174 |
Statement of Responsibility: | Jodie C. Avery, Lisa J. Moran, Vivienne Moore, Renae C. Fernandez, Melissa Whitrow, Nigel Stocks, Tiffany K. Gill, Michael Musker, Michael Davies, Alice Rumbold |
Abstract: | Objective: Although polycystic ovary syndrome (PCOS) is considered a lifelong disorder, very little is understood about the diagnosis and impact of this condition in women outside of the peak reproductive years. We examined the frequency of diagnosed PCOS and concurrent health conditions in women across the lifespan. Methods: Data were analysed from 1509 women aged 15–95 years participating in a cross-sectional, face-to-face population survey in South Australia, 2015. We assessed the prevalence of PCOS in 10-year age groups and the frequency of comorbidities in women with and without PCOS subgrouped by age (< 45, ≥ 45 years). The main outcome measures were Diagnosed PCOS and other chronic conditions; lifestyle factors. Logistic regression analyses determined the risk of comorbidities in women with PCOS adjusting for age and BMI. Results: Overall prevalence of PCOS was 5.6% (95% confidence interval (CI) 4.6–6.9%), peaking in the 35–44 year age group (9.1%), and lowest in those aged 15–24 (4.1%) or ≥ 65 (3.7%) years. Women with PCOS and aged < 45 years were more likely to report diabetes (16.7% vs. 3.8%), cardiovascular disease (15.5% vs. 7.2%) and arthritis (15.5% vs. 7.2%) than their peers; these differences were diminished in the ≥ 45 year age group. The odds of diabetes and cardiovascular disease were more than doubled among women with PCOS (adjOR 2.23, 95% CI 1.49–4.31; adjOR 3.18, 95% CI 1.31–7.68). Conclusion: PCOS is underdiagnosed in young and post-menopausal women. Diabetes and cardiovascular disease are key comorbidities requiring greater attention in younger women with PCOS. |
Keywords: | Polycystic Ovary Syndrome; Comorbidities; Chronic Health Conditions; Age Factors; Diagnosis |
Description: | Published 6 September 2019 |
Rights: | This is an Open Access article published by World Scientific Publishing Company. It is distributed under the terms of the Creative Commons Attribution- NonCommercial-NoDerivatives 4.0 (CC BY-NC-ND) License which permits use, distribution and reproduction, provided that the original work is properly cited, the use is non-commercial and no modifications or adaptations are made. |
DOI: | 10.1142/S2661318219500154 |
Grant ID: | http://purl.org/au-research/grants/nhmrc/1078444 |
Published version: | https://www.worldscientific.com/doi/10.1142/S2661318219500154 |
Appears in Collections: | Aurora harvest 8 Medicine publications |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
hdl_129014.pdf | Published version | 217.71 kB | Adobe PDF | View/Open |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.