Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/133465
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Full metadata record
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dc.contributor.author | Tong, J. | - |
dc.contributor.author | Lee, K.M. | - |
dc.contributor.author | Liu, X. | - |
dc.contributor.author | Nefzger, C.M. | - |
dc.contributor.author | Vijayakumar, P. | - |
dc.contributor.author | Hawi, Z. | - |
dc.contributor.author | Pang, K.C. | - |
dc.contributor.author | Parish, C.L. | - |
dc.contributor.author | Polo, J.M. | - |
dc.contributor.author | Bellgrove, M.A. | - |
dc.date.issued | 2019 | - |
dc.identifier.citation | Stem Cell Research, 2019; 34:101353-101353 | - |
dc.identifier.issn | 1873-5061 | - |
dc.identifier.issn | 1876-7753 | - |
dc.identifier.uri | https://hdl.handle.net/2440/133465 | - |
dc.description.abstract | Peripheral blood mononuclear cells were donated by a male teenager with clinically diagnosed attention deficit hyperactivity disorder (ADHD) under the Diagnostic and Statistical Manual of Mental Disorders IV criteria and his unaffected male sibling. Induced pluripotent stem cells were developed using integration-free Sendai Reprogramming factors containing OCT4, SOX2, KLF4, and c-MYC. All four iPSC lines displayed pluripotent cell morphology, pluripotency-associated factors at the DNA and protein level, alkaline phosphatase enzymatic activity and a male karyotype of 46, XY. All lines had capacity for in vitro differentiation into all the three germ layers. All were negative for Mycoplasma. | - |
dc.description.statementofresponsibility | Janette Tong, Kyung Min Leea, Xiaodong Liu, Christian M.Nefzger, Prasidhee Vijayakumar, Ziarih Hawi ... et al. | - |
dc.language.iso | en | - |
dc.publisher | Elsevier | - |
dc.rights | © 2018 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/BY-NC-ND/4.0 | - |
dc.source.uri | http://dx.doi.org/10.1016/j.scr.2018.11.014 | - |
dc.subject | Leukocytes, Mononuclear | - |
dc.subject | Cell Line | - |
dc.subject | Humans | - |
dc.subject | Cell Culture Techniques | - |
dc.subject | Family | - |
dc.subject | Siblings | - |
dc.subject | Attention Deficit Disorder with Hyperactivity | - |
dc.subject | Adolescent | - |
dc.subject | Australia | - |
dc.subject | Male | - |
dc.subject | Induced Pluripotent Stem Cells | - |
dc.subject | Kruppel-Like Factor 4 | - |
dc.subject | White People | - |
dc.subject.mesh | Leukocytes, Mononuclear | - |
dc.subject.mesh | Cell Line | - |
dc.subject.mesh | Humans | - |
dc.subject.mesh | Cell Culture Techniques | - |
dc.subject.mesh | Family | - |
dc.subject.mesh | Siblings | - |
dc.subject.mesh | Attention Deficit Disorder with Hyperactivity | - |
dc.subject.mesh | Adolescent | - |
dc.subject.mesh | European Continental Ancestry Group | - |
dc.subject.mesh | Australia | - |
dc.subject.mesh | Male | - |
dc.subject.mesh | Induced Pluripotent Stem Cells | - |
dc.title | Generation of four iPSC lines from peripheral blood mononuclear cells (PBMCs) of an attention deficit hyperactivity disorder (ADHD) individual and a healthy sibling in an Australia-Caucasian family | - |
dc.type | Journal article | - |
dc.identifier.doi | 10.1016/j.scr.2018.11.014 | - |
dc.relation.grant | http://purl.org/au-research/grants/nhmrc/1112452 | - |
pubs.publication-status | Published | - |
dc.identifier.orcid | Polo, J.M. [0000-0002-2531-778X] | - |
Appears in Collections: | Medical Sciences publications |
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hdl_133465.pdf | Published version | 919.71 kB | Adobe PDF | View/Open |
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