Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/135541
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Type: | Journal article |
Title: | Caged-Sphere Optofluidic Sensors: Whispering Gallery Resonators in Wicking Microfluidics |
Author: | Riesen, N. Peterkovic, Z.Q. Guan, B. François, A. Lancaster, D.G. Priest, C. |
Citation: | Sensors, 2022; 22(11):4135-1-4135-11 |
Publisher: | MDPI AG |
Issue Date: | 2022 |
ISSN: | 1424-8220 1424-8220 |
Statement of Responsibility: | Nicolas Riesen, Zane Q. Peterkovic, Bin Guan, Alexandre François, David G. Lancaster, and Craig Priest |
Abstract: | The rapid development of optofluidic technologies in recent years has seen the need for sensing platforms with ease-of-use, simple sample manipulation, and high performance and sensitivity. Herein, an integrated optofluidic sensor consisting of a pillar array-based open microfluidic chip and caged dye-doped whispering gallery mode microspheres is demonstrated and shown to have potential for simple real-time monitoring of liquids. The open microfluidic chip allows for the wicking of a thin film of liquid across an open surface with subsequent evaporation-driven flow enabling continuous passive flow for sampling. The active dye-doped whispering gallery mode microspheres placed between pillars, avoid the use of cumbersome fibre tapers to couple light to the resonators as is required for passive microspheres. The performance of this integrated sensor is demonstrated using glucose solutions (0.05–0.3 g/mL) and the sensor response is shown to be dynamic and reversible. The sensor achieves a refractive index sensitivity of ~40 nm/RIU, with Q-factors of ~5 × 103 indicating a detection limit of ~3 × 10−3 RIU (~20 mg/mL glucose). Further enhancement of the detection limit is expected by increasing the microsphere Q-factor using high-index materials for the resonators, or alternatively, inducing lasing. The integrated sensors are expected to have significant potential for a host of downstream applications, particularly relating to point-of-care diagnostics. |
Keywords: | resonators; integrated optics devices; biological sensing and sensors |
Rights: | © 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/). |
DOI: | 10.3390/s22114135 |
Grant ID: | http://purl.org/au-research/grants/arc/IH150100028 |
Published version: | http://dx.doi.org/10.3390/s22114135 |
Appears in Collections: | Physics publications |
Files in This Item:
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hdl_135541.pdf | Published version | 2.19 MB | Adobe PDF | View/Open |
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