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https://hdl.handle.net/2440/139404
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Type: | Journal article |
Title: | Noninvasive and Microinvasive Nanoscale Drug Delivery Platforms for Hard Tissue Engineering |
Author: | Stoilov, B. Truong, V.K. Gronthos, S. Vasilev, K. |
Citation: | ACS Applied Bio Materials, 2023; 6(8):2925-2943 |
Publisher: | American Chemical Society (ACS) |
Issue Date: | 2023 |
ISSN: | 2576-6422 2576-6422 |
Statement of Responsibility: | Borislav Stoilov, Vi Khanh Truong, Stan Gronthos, and Krasimir Vasilev |
Abstract: | Bone tissue plays a crucial role in protecting internal organs and providing structural support and locomotion of the body. Treatment of hard tissue defects and medical conditions due to physical injuries, genetic disorders, aging, metabolic syndromes, and infections is more often a complex and drawn out process. Presently, dealing with hard-tissue-based clinical problems is still mostly conducted via surgical interventions. However, advances in nanotechnology over the last decades have led to shifting trends in clinical practice toward noninvasive and microinvasive methods. In this review article, recent advances in the development of nanoscale platforms for bone tissue engineering have been reviewed and critically discussed to provide a comprehensive understanding of the advantages and disadvantages of noninvasive and microinvasive methods for treating medical conditions related to hard tissue regeneration and repair. |
Keywords: | Nanoscale nanoparticles microinvasive noninvasive hard tissue bone tissue tissue engineering drug delivery system |
Rights: | © 2023 American Chemical Society |
DOI: | 10.1021/acsabm.3c00095 |
Grant ID: | http://purl.org/au-research/grants/nhmrc/GNT1194466 |
Published version: | http://dx.doi.org/10.1021/acsabm.3c00095 |
Appears in Collections: | Molecular and Biomedical Science publications |
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