Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/140527
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Type: | Journal article |
Title: | Development of a glass-based imaging phantom to model the optical properties of human tissue |
Author: | Yang, M. Wei, Y. Reineck, P. Ebendorff-Heidepriem, H. Li, J. McLaughlin, R. |
Citation: | Biomedical Optics Express, 2024; 15(1):346-359 |
Publisher: | Optica Publishing Group |
Issue Date: | 2024 |
ISSN: | 2156-7085 2156-7085 |
Statement of Responsibility: | Mingze Yang, Yunle Wei, Philipp Reineck, Heike Ebendorff-Heidepriem, Jiawen Li, And Robert A. McLaughlin |
Abstract: | The fabrication of a stable, reproducible optical imaging phantom is critical to the assessment and optimization of optical imaging systems. We demonstrate the use of an alternative material, glass, for the development of tissue-mimicking phantoms. The glass matrix was doped with nickel ions to approximate the absorption of hemoglobin. Scattering levels representative of human tissue were induced in the glass matrix through controlled crystallization at elevated temperatures. We show that this type of glass is a viable material for creating tissue-mimicking optical phantoms by providing controlled levels of scattering and absorption with excellent optical homogeneity, long-term stability and reproducibility. |
Keywords: | optical imaging phantom optical imaging systems optimization |
Rights: | © 2024 Published by Optica Publishing Group under the terms of the Creative Commons Attribution 4.0 License. Further distribution of this work must maintain attribution to the author(s) and the published article’s title, journal citation, and DOI. |
DOI: | 10.1364/boe.504774 |
Grant ID: | http://purl.org/au-research/grants/arc/DE200100279 http://purl.org/au-research/grants/arc/CE140100003 http://purl.org/au-research/grants/arc/DP210102442 http://purl.org/au-research/grants/nhmrc/2001646 http://purl.org/au-research/grants/nhmrc/2002254 http://purl.org/au-research/grants/nhmrc/2008462 http://purl.org/au-research/grants/nhmrc/2022337 http://purl.org/au-research/grants/nhmrc/1178912 |
Published version: | http://dx.doi.org/10.1364/boe.504774 |
Appears in Collections: | Research Outputs |
Files in This Item:
File | Description | Size | Format | |
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hdl_140527.pdf | Published version | 5.57 MB | Adobe PDF | View/Open |
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