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Issue Date
Title
Author(s)
2004
A new simple diagnostic assay for the identification of the major CYP2D6 genotypes by DNA sequencing analysis
James, H.
;
Coller, J.
;
Gillis, D.
;
Bahnisch, J.
;
Sallustio, B.
;
Somogyi, A.
2007
Carboxylic acid drug-induced DNA nicking in HEK293 cells expressing human UDP-glucuronosyltransferases: Role of acyl glucuronide metabolites and glycation pathways
Southwood, H.
;
DeGraaf, Y.
;
MacKenzie, P.
;
Miners, J.
;
Burcham, P.
;
Sallustio, B.
2004
Evidence that unsaturated fatty acids are potent inhibitors of renal UDP-glucuronosyltransferases (UGT): kinetic studies using human kidney cortical microsomes and recombinant UGT1A9 and UGT2B7
Toutsikos, P.
;
Miners, J.
;
Stapleton, A.
;
Thomas, A.
;
Sallustio, B.
;
Knights, K.
2005
Validation of a high-performance liquid chromatography method for the measurement of mycophenolic acid and its glucuronide metabolites in plasma
Westley, I.
;
Sallustio, B.
;
Morris, R.
2008
Steady-state pharmacokinetics of the enantiomers of perhexiline in CYP2D6 poor and extensive metabolizers administered Rac-perhexiline
Davies, B.
;
Herbert, M.
;
Coller, J.
;
Somogyi, A.
;
Milne, R.
;
Sallustio, B.
2007
Effect of CYP2D6 metabolizer status on the disposition of the (+) and (-) enantiomers of perhexiline in patients with myocardial ischaemia
Inglis, S.
;
Herbert, M.
;
Davies, B.
;
Coller, J.
;
James, H.
;
Horowitz, J.
;
Morris, R.
;
Milne, R.
;
Somogyi, A.
;
Sallustio, B.
2004
Optimisation of the comet genotoxicity assay in freshly isolated murine hepatocytes: detection of strong in vitro DNA damaging properties for styrene
Fontaine, F.
;
DeGraaf, Y.
;
Ghaoui, R.
;
Sallustio, B.
;
Edwards, J.
;
Burcham, P.
2005
Evaluation of the immunotech cyclosporine direct radioimmunoassay for the determination of whole-blood cyclosporine in renal transplant patients
Wesley, I.
;
Sallustio, B.
;
Morris, R.
2004
Clinical inhibition of CYP2D6-catalysed metabolism by the antianginal agent perhexiline
Davies, B.
;
Coller, J.
;
James, H.
;
Gillis, D.
;
Somogyi, A.
;
Horowitz, J.
;
Morris, R.
;
Sallustio, B.
2002
Pharmacokinetics of the antianginal agent perhexiline: relationship between metabolic ratio and steady-state dose
Sallustio, B.
;
Westley, I.
;
Morris, R.
Discover
Author
6
Morris, R.
5
Coller, J.
5
Somogyi, A.
4
Davies, B.
3
James, H.
3
Milne, R.
2
Burcham, P.
2
DeGraaf, Y.
2
Gillis, D.
2
Herbert, M.
.
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Subject
6
Perhexiline
5
Cardiovascular Agents
5
Male
4
Cytochrome P-450 CYP2D6
3
Adult
3
Aged
3
Chromatography, High Pressure Liquid
3
Enzyme Inhibitors
3
Female
3
Metabolic Clearance Rate
.
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