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https://hdl.handle.net/2440/17397
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dc.contributor.author | Cleland, L. | - |
dc.contributor.author | Gibson, R. | - |
dc.contributor.author | Pedler, J. | - |
dc.contributor.author | James, M. | - |
dc.date.issued | 2005 | - |
dc.identifier.citation | Lipids, 2005; 40(10):995-998 | - |
dc.identifier.issn | 0024-4201 | - |
dc.identifier.issn | 1558-9307 | - |
dc.identifier.uri | http://hdl.handle.net/2440/17397 | - |
dc.description | The original publication can be found at www.springerlink.com | - |
dc.description.abstract | Flaxseed, echium, and canola oils contain α-linolenic acid (18:3n-3, ALA) in a range of concentrations. To examine their effect on elevating cardiac levels of long-chain n-3 FA, diets based on these n-3-containing vegetable oils were fed to rats for 4 wk. Sunflower oil, which contains little ALA, was a comparator. Despite canola oil having the lowest ALA content of the three n-3-containing vegetable oils, it was the most potent for elevating DHA (22:6n-3) levels in rat hearts and plasma. However, the relative potencies of the dietary oils for elevation of EPA (20:5n-3) in heart and plasma followed the same rank order as their ALA content, i.e., flaxseed > echium > canola > sunflower oil. This paradox may be explained by lower ALA intake leading to decreased competition for Δ6 desaturase activity between ALA and the 24:5n-3 FA precursor to DHA formation. | - |
dc.description.statementofresponsibility | Leslie G. Cleland, Robert A. Gibson, Janet Pedler, and Michael J. James | - |
dc.language.iso | en | - |
dc.publisher | Amer Oil Chemists Soc A O C S Press | - |
dc.source.uri | http://www.springerlink.com/content/g10q657453442411/fulltext.pdf | - |
dc.subject | Myocardium | - |
dc.subject | Heart | - |
dc.subject | Animals | - |
dc.subject | Rats | - |
dc.subject | Dietary Fats, Unsaturated | - |
dc.subject | Fatty Acids, Omega-3 | - |
dc.subject | alpha-Linolenic Acid | - |
dc.subject | Docosahexaenoic Acids | - |
dc.subject | Eicosapentaenoic Acid | - |
dc.subject | Fatty Acids | - |
dc.subject | Fatty Acids, Unsaturated | - |
dc.subject | Arachidonic Acid | - |
dc.subject | Fatty Acids, Omega-6 | - |
dc.subject | Phospholipids | - |
dc.subject | Plant Oils | - |
dc.subject | Female | - |
dc.title | Paradoxical effect of n-3-containing vegetable oils on long-chain n-3 fatty acids in rat heart | - |
dc.type | Journal article | - |
dc.identifier.doi | 10.1007/s11745-005-1461-6 | - |
pubs.publication-status | Published | - |
dc.identifier.orcid | Gibson, R. [0000-0002-8750-525X] | - |
dc.identifier.orcid | James, M. [0000-0002-4918-2998] | - |
Appears in Collections: | Aurora harvest 2 Paediatrics publications |
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