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Please use this identifier to cite or link to this item: https://hdl.handle.net/2440/2470
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dc.contributor.authorMickan, S.-
dc.contributor.authorMenikh, A.-
dc.contributor.authorLiu, H.-
dc.contributor.authorMannella, C.-
dc.contributor.authorMacColl, R.-
dc.contributor.authorAbbott, D.-
dc.contributor.authorMunch, J.-
dc.contributor.authorZhang, X.-
dc.date.issued2002-
dc.identifier.citationPhysics in Medicine and Biology, 2002; 47(21):3789-3795-
dc.identifier.issn0031-9155-
dc.identifier.issn1361-6560-
dc.identifier.urihttp://hdl.handle.net/2440/2470-
dc.description© 2002 IOP Publishing-
dc.description.abstractWe report the first use of differential terahertz time-domain spectroscopy for bioaffinity sensing. Binding is observed by measuring the transmission of a thin layer of biotin bound to the sensor protein avidin. We demonstrate the THz wave transmission of a sub-micron-thick film and sensitivity to 0.1 µg cm−2 of biotin. These results point the way for a host of biosensor applications using T-rays, or pulsed far-infrared (FIR) radiation.-
dc.description.statementofresponsibilitySamuel P Mickan, Abdellah Menikh, Haibo Liu, Carmen A Mannella, Robert MacColl, Derek Abbott, Jesper Munch and X-C Zhang-
dc.language.isoen-
dc.publisherIOP Publishing Ltd-
dc.source.urihttp://www.iop.org/EJ/abstract/0031-9155/47/21/317/-
dc.subjectMacromolecular Substances-
dc.subjectAvidin-
dc.subjectAffinity Labels-
dc.subjectMembranes, Artificial-
dc.subjectSensitivity and Specificity-
dc.subjectRefractometry-
dc.subjectSpectrum Analysis-
dc.subjectBiosensing Techniques-
dc.subjectProtein Binding-
dc.subjectBiotin-
dc.subjectElectromagnetic Phenomena-
dc.subjectSurface Properties-
dc.subjectMicrowaves-
dc.subjectEquipment Design-
dc.titleLabel-free bioaffinity detection using terahertz technology-
dc.typeJournal article-
dc.identifier.doi10.1088/0031-9155/47/21/317-
pubs.publication-statusPublished-
dc.identifier.orcidAbbott, D. [0000-0002-0945-2674]-
Appears in Collections:Aurora harvest 2
Electrical and Electronic Engineering publications
Environment Institute publications
Physics publications

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