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https://hdl.handle.net/2440/40290
Type: | Journal article |
Title: | The RADI™ PressureWire® high-sensitivity thermistor and culprit lesion temperature in patients with acute coronary syndromes |
Other Titles: | The RADI(TM) PressureWire (R) high-sensitivity thermistor and culprit lesion temperature in patients with acute coronary syndromes |
Author: | Worthley, S. Farouque, H. Worthley, M. Baldi, M. Chew, D. Meredith, I. |
Citation: | Journal of Invasive Cardiology, 2006; 18(11):528-531 |
Publisher: | Health Management Publications Inc |
Issue Date: | 2006 |
ISSN: | 1042-3931 1557-2501 |
Statement of Responsibility: | Stephen Worthley, Omar Farouque, Matthew Worthley, Mauro Baldi, Derek Chew, Ian Meredith |
Abstract: | <h4>Background</h4>Patients with acute coronary syndromes (ACS) have been shown to have a local increase in culprit lesion temperature of at least 0.5 degrees Celcius using a specialized thermography catheter. However, this device is unique, not clinically available and unable to provide information other than temperature. The 0.014-inch Radi PressureWire XT (RPW) contains a high-sensitivity thermistor in the sensor that has a sensitivity of 0.1 degrees Celcius. We evaluated the ability of the RPW to detect an increase in plaque temperature in patients with ACS.<h4>Methods and results</h4>Patients with ACS and a culprit lesion of > 70% stenosis and who were candidates for percutaneous coronary intervention (PCI) were eligible (n = 20). Fractional flow reserve (FFR) post-adenosine administration and temperature estimations were performed prior to PCI. All demographic data are presented as mean +/- SD, and temperature data (using delta temperature from baseline) as mean +/- SEM. Fifteen men and 5 women were enrolled (age 59.5 +/- 11.6 years). The FFR pre-PCI was 0.65 +/- 0.06, consistent with hemodynamically significant stenoses. The baseline delta temperature was 0.00 +/- 0.01 degrees Celcius. The delta temperature at the culprit lesion was -0.02 +/- 0.01 degrees Celcius (p = NS), a result below the resolution of the thermistor. Post-PCI, the FFR was 0.95 +/- 0.01 (p < 0.0001).<h4>Conclusions</h4>The RPW was unable to detect any temperature increase in patients with ACS. |
Keywords: | Humans Myocardial Infarction Coronary Angiography Thermography Electrocardiography Body Temperature Treatment Outcome Analysis of Variance Probability Risk Assessment Sensitivity and Specificity Prospective Studies Equipment Design Equipment Safety Vascular Patency Coronary Circulation Aged Middle Aged Female Male Angioplasty, Balloon, Coronary Cardiac Catheterization |
Appears in Collections: | Aurora harvest 6 Medicine publications |
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