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https://hdl.handle.net/2440/40423
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Type: | Journal article |
Title: | Domiciliary oxygen for interstitial lung disease |
Author: | Crockett, A. Cranston, J. Antic, N. |
Citation: | Cochrane Database of Systematic Reviews, 2001; 2001(3):Art no. CD002883- |
Publisher: | Update Software Ltd |
Issue Date: | 2001 |
ISSN: | 1469-493X 1464-780X |
Statement of Responsibility: | AJ Crockett, JM Cranston and N Antic |
Abstract: | <h4>Background</h4>Retrospective survival data have suggested poor effectiveness of oxygen therapy in patients with interstitial lung disease (ILD).<h4>Objectives</h4>To determine the effect of domiciliary oxygen therapy on survival and quality of life in patients with a diagnosis of ILD and hypoxaemia.<h4>Search strategy</h4>Randomized Controlled Trials (RCTs) were identified using the Cochrane Airways Group register and the search terms: (home OR domiciliary AND oxygen AND (Interstitial lung disease OR ILD OR pulmonary fibrosis OR IPF)).<h4>Selection criteria</h4>Any randomized controlled trial (RCT) in adult patients with hypoxaemia and ILD that compared long term domiciliary or home oxygen therapy with a control group.<h4>Data collection and analysis</h4>Only one unpublished RCT was identified.<h4>Main results</h4>Only one trial was identified. Mortality for both the oxygen treated and control groups was approximately 91% after 3 years (Peto odds ratio 0.99, 95% confidence intervals 0.16,6.26). The effect of oxygen therapy on quality of life and physiological parameters was not reported.<h4>Reviewer's conclusions</h4>The assumption that home oxygen therapy has a beneficial survival effect in patients with ILD has not been demonstrated in the single RCT identified. |
Keywords: | Humans Lung Diseases, Interstitial Oxygen Inhalation Therapy Confidence Intervals Odds Ratio Quality of Life Home Care Services Randomized Controlled Trials as Topic |
Description: | Copyright © 2008 The Cochrane Collaboration. Published by John Wiley and Sons, Ltd. |
DOI: | 10.1002/14651858.CD002883 |
Published version: | http://dx.doi.org/10.1002/14651858.cd002883 |
Appears in Collections: | Aurora harvest 6 General Practice publications |
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