Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/46438
Citations | ||
Scopus | Web of ScienceĀ® | Altmetric |
---|---|---|
?
|
?
|
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Li, X. | - |
dc.contributor.author | Sun, H. | - |
dc.contributor.author | Zhang, G. | - |
dc.contributor.author | Bi, J. | - |
dc.contributor.author | Ma, G. | - |
dc.contributor.author | Ma, R. | - |
dc.contributor.author | Su, Z. | - |
dc.date.issued | 2005 | - |
dc.identifier.citation | Journal of Separation Science, 2005; 28(17):2363-2369 | - |
dc.identifier.issn | 1615-9306 | - |
dc.identifier.issn | 1615-9314 | - |
dc.identifier.uri | http://hdl.handle.net/2440/46438 | - |
dc.description | The definitive version is available from www.wiley.com | - |
dc.description.abstract | Huperzine A (HupA) and huperzine B (HupB) are two medically important components of Huperzia serrata. It is difficult to obtain high yields of the separation from the plant using conventional liquid extraction and chromatography. However, this study has found that RP chromatography with cyanopropyl (CN) medium was able to separate these two analogs simultaneously from the plant extract with higher resolution. Comparison between a CN medium and a popular C18 medium demonstrated the superiority of the CN over the C18 in resolution for both analytical and preparative separation of HupA and HupB. A preparative process was developed for simultaneous purification of HupA and HupB from H. serrata. The yields on the basis of the mass of the herbal powder for HupA and HupB were 0.019 and 0.008% respectively, which were about 1.9 and 10 times of those reported in the literature. | - |
dc.language.iso | en | - |
dc.publisher | Wiley - V C H Verlag GmbH & Co. KGaA | - |
dc.source.uri | http://www3.interscience.wiley.com/journal/112133420/abstract | - |
dc.subject | Cyanopropyl stationary phase | - |
dc.subject | Huperzine A | - |
dc.subject | Huperzine B | - |
dc.subject | Purification | - |
dc.subject | Resolution | - |
dc.title | A cyanopropyl reversed phase chromatography enables resolution of huperzine A and B on analytical and preparative scales | - |
dc.type | Journal article | - |
dc.identifier.doi | 10.1002/jssc.200500137 | - |
pubs.publication-status | Published | - |
dc.identifier.orcid | Bi, J. [0000-0001-7056-8572] | - |
Appears in Collections: | Aurora harvest 6 Chemical Engineering publications |
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.