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https://hdl.handle.net/2440/51870
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Type: | Journal article |
Title: | A synthesis of the C1-C15 domain of the halichondrins |
Author: | Jackson, K. Henderson, J. Morris, J. Motoyoshi, H. Phillips, A. |
Citation: | Tetrahedron Letters: the international journal for the rapid publication of all preliminary communications in organic chemistry, 2008; 49(18):2939-2941 |
Publisher: | Pergamon-Elsevier Science Ltd |
Issue Date: | 2008 |
ISSN: | 0040-4039 |
Statement of Responsibility: | Katrina L. Jackson, James A. Henderson, Jonathan C. Morris, Hajime Motoyoshi, Andrew J. Phillips |
Abstract: | A concise route to the C1-C15 domain of the halichondrins is described. The key reaction is the conversion of a furfuryl alcohol to a pyranone. The stereocenter of this pyranone serves as the starting point for the other 8 stereocenters. |
DOI: | 10.1016/j.tetlet.2008.03.018 |
Published version: | http://dx.doi.org/10.1016/j.tetlet.2008.03.018 |
Appears in Collections: | Aurora harvest 5 Chemistry publications |
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