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Issue Date
Title
Author(s)
2016
ABCB1 overexpression predicts outcome of CML patients undergoing first-line imatinib treatment
Eadie, L.
;
Hughes, T.
;
White, D.
;
New Directions in Leukaemia Research 2016 Meeting (NDLR) (16 Mar 2016 - 19 Mar 2016 : Noosa, QLD)
2014
Interaction of the efflux transporters ABCB1 and ABCG2 with imatinib, nilotinib, and dasatinib
Eadie, L.
;
Hughes, T.
;
White, D.
2018
ABCC6 plays a significant role in the transport of nilotinib and dasatinib, and contributes to TKI resistance in vitro, in both cell lines and primary patient mononuclear cells
Eadie, L.
;
Dang, P.
;
Goyne, J.
;
Hughes, T.
;
White, D.
;
Maga, G.
2013
Proton pump inhibitors significantly increase the intracellular concentration of nilotinib, but not imatinib in target CML cells
White, D.
;
Eadie, L.
;
Saunders, V.
;
Hiwase, D.
;
Hughes, T.
2008
Dasatinib cellular uptake and efflux in chronic myeloid leukemia cells: therapeutic implications
Hiwase, D.
;
Saunders, V.
;
Hewett, D.
;
Frede, A.
;
Zrim, S.
;
Dang, P.
;
Eadie, L.
;
To, L.
;
Vaz de Melo, J.
;
Kumar, S.
;
Hughes, T.
;
White, D.
2013
Degree of kinase inhibition achieved in vitro by imatinib and nilotinib is decreased by high levels of ABCB1 but not ABCG2
Eadie, L.
;
Saunders, V.
;
Hughes, T.
;
White, D.
2016
ABCB1 Overexpression Is a key initiator of resistance to tyrosine kinase inhibitors in CML cell lines
Eadie, L.
;
Hughes, T.
;
White, D.
;
Eaves, C.
Discover
Author
3
Saunders, V.
2
Dang, P.
2
Hiwase, D.
1
Eaves, C.
1
Frede, A.
1
Goyne, J.
1
Hewett, D.
1
Kumar, S.
1
Maga, G.
1
New Directions in Leukaemia Resea...
.
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Subject
3
Benzamides
3
Humans
3
Imatinib Mesylate
3
Piperazines
3
Pyrimidines
2
Animals
2
ATP Binding Cassette Transporter,...
2
ATP Binding Cassette Transporter,...
2
ATP Binding Cassette Transporter,...
2
ATP-Binding Cassette Transporters
.
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2008