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Results 1-10 of 13 (Search time: 0.002 seconds).
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Issue Date
Title
Author(s)
2002
High frequency of point mutations clustered within the adenosine triphosphate-binding region of BCR/ABL in patients with chronic myeloid leukemia or Ph-positive acute lymphoblastic leukemia who develop imatinib (STI571) resistance
Branford, S.
;
Rudzki, Z.
;
Walsh, S.
;
Grigg, A.
;
Arthur, C.
;
Taylor, K.
;
Herrmann, R.
;
Lynch, K.
;
Hughes, T.
2006
Five-year follow-up of patients receiving imatinib for chronic myeloid leukemia
Druker, B.
;
Guilhot, F.
;
O'Brien, S.
;
Gathmann, I.
;
Kantarjian, H.
;
Gattermann, N.
;
Deininger, M.
;
Silver, R.
;
Goldman, J.
;
Stone, R.
;
Cervantes, F.
;
Hochhaus, A.
;
Powell, B.
;
Gabrilove, J.
;
Rousselot, P.
;
Reiffers, J.
;
Cornelissen, J.
;
Hughes, T.
;
Agis, H.
;
Fischer, T.
;
et al.
2008
Nilotinib (formerly AMN107), a highly selective BCR-ABL tyrosine kinase inhibitor, is active in patients with imatinib-resistant or -intolerant accelerated-phase chronic myelogenous leukemia
le Coutre, P.
;
Ottmann, O.
;
Giles, F.
;
Kim, D.
;
Cortes, J.
;
Gattermann, N.
;
Apperley, J.
;
Larson, R.
;
Abruzzese, E.
;
O'Brien, S.
;
Kuliczkowski, K.
;
Hochhaus, A.
;
Mahon, F.
;
Saglio, G.
;
Gobbi, M.
;
Kwong, Y.
;
Baccarani, M.
;
Hughes, T.
;
Martinelli, G.
;
Radich, J.
;
et al.
2005
Dynamics of chronic myeloid leukaemia
Michor, F.
;
Hughes, T.
;
Iwasa, Y.
;
Branford, S.
;
Shah, N.
;
Sawyers, C.
;
Nowak, M.
2003
Molecular monitoring of chronic myeloid leukemia
Hughes, T.
;
Branford, S.
2003
Imatinib inhibits the in vitro development of the monocyte/macrophage lineage from normal human bone marrow progenitors
Dewar, A.
;
Domaschenz, R.
;
Doherty, K.
;
Hughes, T.
;
Lyons, A.
2003
Frequency of major molecular responses to imatinib or interferon alfa plus cytarabine in newly diagnosed chronic myeloid leukemia
Hughes, T.
;
Kaeda, J.
;
Branford, S.
;
Rudzki, Z.
;
Hochhaus, A.
;
Hensley, M.
;
Gathmann, I.
;
Bolton, A.
;
van Hoomissen, I.
;
Goldman, J.
;
Radich, J.
2004
Clinical resistance to imatinib: mechanisms and implications
Hochhaus, A.
;
Hughes, T.
2009
Impact of baseline BCR-ABL mutations on response to Nilotinib in patients with chronic myeloid leukemia in chronic phase
Hughes, T.
;
Saglio, G.
;
Branford, S.
;
Soverini, S.
;
Kim, J.
;
Muller, M.
;
Martinelli, G.
;
Cortes, J.
;
Beppu, L.
;
Gottardi, E.
;
Dongho, K.
;
Erben, P.
;
Shou, Y.
;
Haque, A.
;
Gallagher, N.
;
Radich, J.
;
Hochhaus, A.
2009
Selecting optimal second-line tyrosine kinase inhibitor therapy for chronic myeloid leukemia patients after imatinib failure: does the BCR-ABL mutation status really matter?
Branford, S.
;
Vaz de Melo, J.
;
Hughes, T.
Discover
Author
7
Branford, S.
5
Hochhaus, A.
3
Radich, J.
3
Rudzki, Z.
2
Arthur, C.
2
Cortes, J.
2
et al.
2
Gathmann, I.
2
Gattermann, N.
2
Goldman, J.
.
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Subject
13
Benzamides
13
Humans
13
Piperazines
13
Pyrimidines
10
Leukemia, Myelogenous, Chronic, B...
7
Antineoplastic Agents
6
Drug Resistance, Neoplasm
6
Male
5
Female
5
Mutation
.
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2002