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PreviewIssue DateTitleAuthor(s)
2019OBI-3424, a novel AKR1c3-activated prodrug, exhibits potent efficacy against preclinical models of T-ALLEvans, K.; Duan, J.X.; Pritchard, T.; Jones, C.D.; McDermott, L.; Gu, Z.; Toscan, C.E.; El-Zein, N.; Mayoh, C.; Erickson, S.W.; Guo, Y.; Meng, F.; Jung, D.; Rathi, K.S.; Roberts, K.G.; Mullighan, C.G.; Shia, C.S.; Pearce, T.; Teicher, B.A.; Smith, M.A.; et al.
2021Optimizing metastatic-cascade-dependent Rac1 targeting in breast cancer: guidance using optical window intravital FRET imagingFloerchinger, A.; Murphy, K.J.; Latham, S.L.; Warren, S.C.; McCulloch, A.T.; Lee, Y.-K.; Stoehr, J.; Mélénec, P.; Guaman, C.S.; Metcalf, X.L.; Lee, V.; Zaratzian, A.; Da Silva, A.; Tayao, M.; Rolo, S.; Phimmachanh, M.; Sultani, G.; McDonald, L.; Mason, S.M.; Ferrari, N.; et al.
2018Inhibition of activin signaling in lung adenocarcinoma increases the therapeutic index of platinum chemotherapyMarini, K.D.; Croucher, D.R.; McCloy, R.A.; Vaghjiani, V.; Gonzalez-Rajal, A.; Hastings, J.F.; Chin, V.; Szczepny, A.; Kostyrko, K.; Marquez, C.; Samantha, W.; Jayasekara, N.; Alamgeer, M.; Boolell, V.; Han, J.Z.R.; Waugh, T.; Lee, H.C.; Oakes, S.R.; Kumar, B.; Harrison, C.A.; et al.
2016GD2-specific CAR T cells undergo potent activation and deletion following antigen encounter but can be protected from activation-induced cell death by PD-1 blockadeGargett, T.; Yu, W.; Dotti, G.; Yvon, E.; Christo, S.; Hayball, J.; Lewis, I.; Brenner, M.; Brown, M.
2013Combined targeting of JAK2 and Bcl-2/Bcl-xL to cure mutant JAK2-driven malignancies and overcome acquired resistance to JAK2 inhibitorsWaibel, M.; Solomon, V.; Knight, D.; Ralli, R.; Kim, S.; Banks, K.; Vidacs, E.; Virely, C.; Sia, K.; Bracken, L.; Collins-Underwood, R.; Drenberg, C.; Ramsey, L.; Meyer, S.; Takiguchi, M.; Dickins, R.; Levine, R.; Ghysdael, J.; Dawson, M.; Lock, R.; et al.
2013Nanoparticles produced by ring-opening metathesis polymerization using norbornenyl-poly(ethylene oxide) as a ligand-free generic platform for highly selective in vivo tumor targetingGueugnon, F.; Denis, I.; Pouliquen, D.; Collette, F.; Delatouche, R.; Héroguez, V.; Grégoire, M.; Bertrand, P.; Blanquart, C.