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https://hdl.handle.net/2440/74648
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DC Field | Value | Language |
---|---|---|
dc.contributor.author | Forbes, B. | - |
dc.contributor.other | A.P.T. Patent and Trade Mark Attorneys | - |
dc.date.issued | 2010 | - |
dc.identifier.uri | http://hdl.handle.net/2440/74648 | - |
dc.description | PATENT: B. Forbes (Assignee: University of Adelaide). WO 2004/007543 A1 (PCT/AU2003/000898) filed Jul 11, 2003; published Jan 22, 2004 | - |
dc.description.abstract | Altered IGFBPs are able to bind IGF but the release is inhibited by resistance to protease cleavage and/or reduced binding to extracellular matrix (ECM). Alterations have been made in IGFBP-2 to the linker domain in particular and two amino acid motifs found to be important for ECM binding. IGF-1 mediated proliferation of cancer cells have been inhibited by the use of these altered IGFBPs. | - |
dc.description.statementofresponsibility | Invented by B. Forbes; assigened to University of Adelaide; A.P.T. Patent and Trade Mark Attorneys agent for inventors. | - |
dc.description.uri | http://www.patentlens.net/patentlens/patent/WO_2004_007543_A1/en/ | - |
dc.language.iso | en | - |
dc.subject | WO 2004/007543 A1 | - |
dc.title | Altered Insulin-Like Growth Factor binding Proteins | - |
dc.type | Patent | - |
dc.contributor.assignee | University of Adelaide | - |
dc.identifier.patent | 4559222 | - |
pubs.publication-status | Published | - |
Appears in Collections: | Aurora harvest 4 Molecular and Biomedical Science publications |
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