Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/74685
Type: | Patent |
Title: | Comparative Genomic Hybridization |
Author: | Hussey, Nicole Dominique Hu, Dong Gui |
Issue Date: | 2009 |
Assignee: | Adelaide Research & Innovation Pty Ltd |
School/Discipline: | School of Paediatrics and Reproductive Health : Obstetrics and Gynaecology |
Contributor: | Phillips Ormonde Fitzpatrick |
Statement of Responsibility: | Invented by N. D. Hussey, D. G. Hu; Assigned to Adelaide Research & Innovation Pty Ltd; Phillips Ormonde Fitzpatrick agents for inventors. |
Abstract: | The present invention relates to a method of comparing at least one chromosome or part thereof from a cell with a first karyotype with the corresponding chromosome or part thereof from a cell with a second karyotype. The method includes the steps of: (a) amplifying DNA from an isolated chromosome or part of an isolated chromosome; (b) attaching the amplified DNA to a solid substrate; (c) amplifying DNA from one or more cells with a first karyotype and amplifying DNA from one or more cells with a second karyotype; (d) labelling the amplified DNA from the one or more cells with a first karyotype with a first label, and labelling the amplified DNA from the one or more cells with a second karyotype with a second label, wherein the first and second labels are detectably different; (e) hybridizing the amplified and labelled DNA from the one or more cells with a first karyotype to the amplified DNA attached to the solid substrate, and hybridizing the amplified and labelled DNA from the one or more cells with a second karyotype to the amplified DNA attached to the solid substrate; and (f) comparing the relative amount of first and second labels hybridized to the amplified DNA attached to the solid substrate. |
Keywords: | AU 2004/225908 B2 |
Description: | PATENT: N. D. Hussey, D. G. Hu (Assignee: Adelaide Research & Innovation Pty Ltd). AU 2004/225908 B2 (WO 2004/088310 A1) filed Apr 2, 2004; published (WIPO) Oct 14, 2004; accepted journal date May 28, 2009. |
Description (link): | http://www.patentlens.net/patentlens/patent/AU_2004_225908_B2/en/ |
Appears in Collections: | Obstetrics and Gynaecology publications |
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