Adelaide Research & Scholarship
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https://hdl.handle.net/2440/75899
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| Type: | Journal article |
| Title: | Trough concentrations of vancomycin: adult therapeutic targets are not appropriate for children |
| Author: | Gordon, C. Thompson, C. Carapetis, J. Turnidge, J. Kilburn, C. Currie, B. |
| Citation: | The Pediatric Infectious Disease Journal, 2012; 31(12):1269-1271 |
| Publisher: | Lippincott Williams & Wilkins |
| Issue Date: | 2012 |
| ISSN: | 0891-3668 1532-0987 |
| Statement of Responsibility: | Claire L. Gordon, Chantelle Thompson, Jonathan R. Carapetis, John Turnidge, Charles Kilburn and Bart J. Currie |
| Abstract: | Despite the need for effective vancomycin therapy, there are few data guiding vancomycin monitoring in children. We reviewed retrospectively vancomycin use in children 1 month to 12 years of age. Initial and adjusted target trough vancomycin concentrations in serum were infrequently achieved regardless of the dosing schedule. Currently recommended trough concentrations need to be re-examined with a more detailed pharmacokinetic study in children. |
| Keywords: | vancomycin Staphylococcus aureus therapeutic drug monitoring |
| Rights: | Copyright: © 2012 Lippincott Williams & Wilkins, Inc. |
| DOI: | 10.1097/INF.0b013e31826a3eaf |
| Published version: | http://dx.doi.org/10.1097/inf.0b013e31826a3eaf |
| Appears in Collections: | Aurora harvest Molecular and Biomedical Science publications |
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