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https://hdl.handle.net/2440/9643
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DC Field | Value | Language |
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dc.contributor.author | Pearce, S. | - |
dc.contributor.author | Miles, T. | - |
dc.contributor.author | Thompson, P. | - |
dc.contributor.author | Nordstrom, M. | - |
dc.date.issued | 2003 | - |
dc.identifier.citation | The Journal of Physiology, 2003; 549(2):583-596 | - |
dc.identifier.issn | 0022-3751 | - |
dc.identifier.issn | 1469-7793 | - |
dc.identifier.uri | http://hdl.handle.net/2440/9643 | - |
dc.description | Copyright © 2003 The Physiological Society The definitive version is available at www.blackwell-synergy.com | - |
dc.description.abstract | The corticobulbar inputs to single masseter motoneurons from the contra- and ipsilateral motor cortex were examined using focal transcranial magnetic stimulation (TMS) with a figure-of-eight stimulating coil. Fine-wire electrodes were inserted into the masseter muscle of six subjects, and the responses of 30 motor units were examined. All were tested with contralateral TMS, and 87 % showed a short-latency excitation in the peristimulus time histogram at 7.0 ± 0.3 ms. The response was a single peak of 1.5 ± 0.2 ms duration, consistent with monosynaptic excitation via a single D- or I1-wave volley elicited by the stimulus. Increased TMS intensity produced a higher response probability (n = 13, paired t test, P< 0.05) but did not affect response latency. Of the remaining motor units tested with contralateral TMS, 7 % did not respond at intensities tested, and 7 % had reduced firing probability without any preceding excitation. Sixteen of these motor units were also tested with ipsilateral TMS and four (25 %) showed short-latency excitation at 6.7 ± 0.6 ms, with a duration of 1.5 ± 0.3 ms. Latency and duration of excitatory peaks for these four motor units did not differ significantly with ipsilateral vs. contralateral TMS (paired t tests, P> 0.05). Of the motor units tested with ipsilateral TMS, 56 % responded with a reduced firing probability without a preceding excitation, and 19 % did not respond. These data suggest that masseter motoneurons receive monosynaptic input from the motor cortex that is asymmetrical from each hemisphere, with most low threshold motoneurons receiving short-latency excitatory input from the contralateral hemisphere only. | - |
dc.description.statementofresponsibility | Sophie L. Pearce, Timothy S. Miles, Philip D. Thompson and Michael A. Nordstrom | - |
dc.language.iso | en | - |
dc.publisher | Cambridge Univ Press | - |
dc.source.uri | http://jp.physoc.org/cgi/content/abstract/549/2/583 | - |
dc.subject | Masseter Muscle | - |
dc.subject | Motor Cortex | - |
dc.subject | Motor Neurons | - |
dc.subject | Humans | - |
dc.subject | Probability | - |
dc.subject | Electric Stimulation | - |
dc.subject | Differential Threshold | - |
dc.subject | Dominance, Cerebral | - |
dc.subject | Reaction Time | - |
dc.subject | Electrophysiology | - |
dc.subject | Adult | - |
dc.subject | Female | - |
dc.subject | Male | - |
dc.subject | Transcranial Magnetic Stimulation | - |
dc.title | Responses of single motor units in human masseter to transcranial magnetic stimulation of either hemisphere | - |
dc.type | Journal article | - |
dc.identifier.doi | 10.1113/jphysiol.2002.035352 | - |
pubs.publication-status | Published | - |
Appears in Collections: | Aurora harvest Medicine publications Molecular and Biomedical Science publications |
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